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Allergic Bronchopulmonary Aspergillosis (ABPA)

A 37-year-old asthmatic man presents with worsening wheezing and productive cough with brown mucus plugs. Labs: total IgE >1000 IU/mL, eosinophilia, positive Aspergillus-specific IgE. Chest CT shows central bronchiectasis.

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Oral corticosteroids for acute management

Clinical + high total IgE + Aspergillus-specific IgE + radiology

Itraconazole or voriconazole to reduce fungal burden

Pulmonology follow-up with IgE monitoring and chest imaging

Omalizumab for refractory asthma/ABPA

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