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⏱️ 240s

🌱 Beginner Level — 0 / 60

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Hematologic Emergencies — Tumor Lysis Syndrome (TLS)

A 45-year-old man with newly diagnosed Burkitt lymphoma starts chemotherapy. Within 12 hours, develops oliguria, nausea, and arrhythmia. Labs: K+ 6.2, phosphate 7.0, Ca2+ 6.8, uric acid 13, Cr 2.3.

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💡 Hint: Correct order adjusted to match available steps.

Rasburicase for uric acid >8 mg/dL or high-risk TLS

Avoid routine calcium replacement in asymptomatic hypocalcemia

Aggressive IV hydration

Dialysis if refractory electrolyte disturbances or AKI

Allopurinol for prophylaxis (not treatment)

Manage hyperkalemia, hyperphosphatemia, hypocalcemia

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