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🌱 Beginner Level — 0 / 50

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Thrombotic Thrombocytopenic Purpura (TTP)

A 42-year-old woman presents with confusion, fever, renal dysfunction, thrombocytopenia, and hemolytic anemia. Labs: schistocytes, ↑LDH, low haptoglobin. ADAMTS13 activity <10% with inhibitor present.

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💡 Hint: Correct order adjusted to match available steps.

Urgent plasma exchange (PEX)

High-dose corticosteroids

Avoid prophylactic platelet transfusions

Add caplacizumab (anti-vWF nanobody) if available

Add rituximab for refractory/recurrent disease

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